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Canine Science

Scientific Research

When evaluating the science supporting a product, it’s important to ascertain the level of testing, with the most detailed level being double-blind placebo controlled clinical trials. These trials are then published in independent peer- reviewed medical, pharmacology and health journals.

Rose-Hip Vital® Canine is supported by over 30 scientific papers including 9 clinical trials, unique to Rose-Hip Vital® products, which have been published in peer reviewed journals internationally and is now acknowledged as the leader in the field of manufactured Rosehip products.

GOPO® – A Vital Difference

Thanks to patented extraction and drying processes, Rose-Hip Vital® Canine contains the active compound GOPO® (glycoside of mono and diglycerol).

Some white blood cells contain granulocytes which enable them to ‘clean’ an inflamed joint by destroying the bacteria in it.  Too many of these white blood cells wear down tissue cartilage. In large numbers they can also produce chemical enzymes and toxic free-radicals which cause even more tissue damage. Accumulation of white blood cells combined with the release of chemical substances causes joint pain and inflammation. The more inflamed a joint becomes, the more the white blood cells are attracted to it – a painful cycle.

GOPO® discourages large numbers of white blood cells from accumulating in the joint, thereby breaking the cycle of joint inflammation and alleviating pain.

THE SCIENCE

Results from a randomized, placebo-controlled trial published in the Osteoarthritis and Cartilage 18, supplement 2 (2010) suggests Rose-Hip Vital® Canine shows anti-inflammatory properties in dogs and works as a strong antioxidant. The study showed statistically significant improvements to the general wellbeing of dogs, with the study testing for motivation, mood, working capacity, cooperation, speed and fur quality. Three-month treatment resulted in a significant decline in total white blood cell count – indicating that Rose-Hip Vital® Canine works as an anti-inflammatory in dogs.

Rosehip has been the subject of a significant new study published in the of medical journal Phytomedicine – Rosehip herbal remedy in patients with Rheumatoid Arthritis – a randomised controlled trial – which has shown that patients with Rheumatoid Arthritis may benefit from additional treatment with Rosehip powder with Galactolipid (GOPO®).
Phytomedicine 2010

A presentation by Joseph Schwager, Phd, at the APLAR conference Asia Pacific League of Associations for Rheumatology conference in Japan titled The Galactolipid GOPO Mediates Beneficial Effects of Rose Hip on Arthritis by Reducing Chemokine and Interleukin Production in Macrophages and Chondrocytes, showed that an active compound, when isolated from the Rosehip, may play a role in assisting in the rebuilding and protection of cartilage.
Aplar 2008

A study released by Arasalan Kharazmi, Phd, at OARSI (Osteoarthritis Research Society International) – Laboratory and preclinical studies on the anti-inflammatory and anti-oxidant properties of rosehip powder – Identification and characterisation of the active component GOPO® – demonstrate through assessment of in vitro studies that rosehip powder exhibits anti-inflammatory as well as anti-oxidant activities.
Oarsi 2008

A trial published in the Scandinavian Journal of Rheumatology – A Powder made from seeds and shells of Rosehip Subspecies (Rosa Canina L) reduces the symptoms of Knee and Hip Osteoarthritis: a Randomised, Double-Blind, Placebo Controlled Trial – showed that 82% of patients reported a reduction in pain after 3 weeks of active treatment with GOPO®. Pain was alleviated to such an extent that 40% reduced their consumption of parecetamol.
Journal of Rheumatology, 2005

Improve your dog’s joint health and wellbeing

Reduce inflammation, protect cartilage and boost immunity

Rose-Hip Vital® Canine is a plant-based anti-inflammatory and immune system support for your dog’s joint health and general well-being. Made from Rosehips manufactured with patented processes, Rose-Hip Vital® Canine is scientifically and clinically proven to reduce inflammation, protect cartilage, improve general health and improve performance.

Patented extraction and drying processes isolate and activate the compound GOPO® which has scientifically proven anti-inflammatory and antioxidative properties. GOPO® works by stopping excess white blood cells from gathering around inflamed tissue, thereby helping to break the cycle of inflammation and protect cartilage. Rosehip products that do not contain GOPO® have not been shown to have anti-inflammatory properties.

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